|
Product
|
IL-8/CXCL8 (8-79aa), Human
|
|
Cat#
|
101-27-158A
|
|
Sequence
|
The sequence of the
first five N-terminal amino
acids has been found
to be Ala-Val-Leu-Pro-Arg.
|
|
Unit/Weight
|
10 μg
|
|
Unit Price
|
$68.00
|
|
Description
|
Interleukin-8 (IL-8) belongs to the neutrophil-specific CXC family of chemokines. It is one of the initial cytokines released from a variety of cell types, including T cells, endothelial cells and fibroblasts, in response to an inflammatory stimulus and acts by recruiting neutrophils, T-cells and basophils to the site of inflammation. Elevated Interleukin-8 (IL-8) levels are associated with the onset of a variety of disease states.
Human Interleukin-8 (IL-8) (3-79) , produced in E. coli, is a single, non-glycosylated polypeptide chain containing 77 amino acids and having a molecular mass of 8,904 Da.
|
|
Molecular Weight
|
9,000 Da+/-10%, determined by reduced SDS-PAGE
|
|
Purity
|
The purity of recombinant Human Interleukin-8 (IL-8) is greater than 95.0%, as determined by the following methods:
(a) RP-HPLC analysis
(b) Reducing and non-reducing SDS-PAGE silver-stained gel analysis
|
|
Storage
|
Although lyophilized Recombinant Human Interleukin-8 (IL-8)/77 can remain stable at room temperature for three weeks, it is best stored desiccated below -18°C. After reconstitution, Recombinant Human Interleukin-8 (IL-8)/77 may be stored at 4°C for up to seven days and below -18°C for longer periods. For long-term storage it is recommended that a carrier protein (0.1% HSA or BSA) be added. Please avoid freeze-thaw cycles.
|
|