Product
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IL-8/CXCL8 (8-79aa), Human
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Cat#
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101-27-158B
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Sequence
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The sequence of the
first five N-terminal amino
acids has been found
to be Ala-Val-Leu-Pro-Arg.
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Unit/Weight
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50 μg
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Unit Price
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$258.00
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Description
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Interleukin-8 (IL-8) belongs to the neutrophil-specific CXC family of chemokines. It is one of the initial cytokines released from a variety of cell types, including T cells, endothelial cells and fibroblasts, in response to an inflammatory stimulus and acts by recruiting neutrophils, T-cells and basophils to the site of inflammation. Elevated Interleukin-8 (IL-8) levels are associated with the onset of a variety of disease states.
Human Interleukin-8 (IL-8) (3-79) , produced in E. coli, is a single, non-glycosylated polypeptide chain containing 77 amino acids and having a molecular mass of 8,904 Da.
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Molecular Weight
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9,000 Da+/-10%, determined by reduced SDS-PAGE
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Purity
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The purity of recombinant Human Interleukin-8 (IL-8) is greater than 95.0%, as determined by the following methods:
(a) RP-HPLC analysis
(b) Reducing and non-reducing SDS-PAGE silver-stained gel analysis
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Storage
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Although lyophilized Recombinant Human Interleukin-8 (IL-8)/77 can remain stable at room temperature for three weeks, it is best stored desiccated below -18°C. After reconstitution, Recombinant Human Interleukin-8 (IL-8)/77 may be stored at 4°C for up to seven days and below -18°C for longer periods. For long-term storage it is recommended that a carrier protein (0.1% HSA or BSA) be added. Please avoid freeze-thaw cycles.
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