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Product
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6Ckine/CCL21, Rat
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Cat#
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101-27-146A
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Sequence
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SDGGGQDCCL RYSQKKIPYN IVRGYRKQEP SLGCPIPAIL
FAPRKQSQPE LCANPEEAWV QKLMRRLDQP PAPGKQNCRK NRGTSKSGKK
GRGSKGCKGT EQTDSKRVSQ
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Unit/Weight
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50 μg
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Unit Price
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$152.00
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Description
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Chemokine (C-C motif) ligand 21 (CCL21) is a small cytokine belonging to the CC chemokine family. This chemokine is also known as 6Ckine, exodus-2, and secondary lymphoid-tissue chemokine (SLC). CCL21 contains four conserved cysteines characteristic of ?chemokines plus two additional cysteines in an unusually long carboxyl-terminal domain. It is expressed in lymphatic endothelial cells and the spleen. CCL21 chemoattracts T and B lymphocytes and inhibits hematopoiesis. It can signal through the CCR7 receptor.
Recombinant rat 6Ckine/CCL21 produced in CHO cells is a polypeptide chain containing 120 amino acids. A fully biologically active molecule, rr6Ckine/CCL21 has a molecular mass of 12 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at Pepmic.
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Molecular Weight
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12 kDa, observed by reducing SDS-PAGE.
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Purity
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> 95% as analyzed by SDS-PAGE.
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Storage
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Lyophilized recombinant Rat 6Ckine/CCL21 remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Rat 6Ckine/CCL21 should be stable up to 1 week at 4°C or up to 3 months at -20°C. For long term storage, it is recommended that a carrier protein (eg. 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.
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