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Product
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MPIF/CCL23(aa46-120), Human
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Cat#
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101-27-143B
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Sequence
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RFHATSADCC ISYTPRSIPC SLLESYFETN SECSKPGVIF
LTKKGRRFCA NPSDKQVQVC VRMLKLDTRI KTRKN
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Unit/Weight
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25 μg
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Unit Price
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$92.00
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Description
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Myeloid progenitor inhibitory factor 1 (MPIF-1), also known as Chemokine (C-C motif) ligand 23 (CCL23) is a small cytokine belonging to the CC chemokine family. MPIF-1 is predominantly expressed in lung and liver tissue, but is also found in bone marrow and placenta. It is also expressed in some cell lines of myeloid origin. It is highly chemotactic for resting T cells and monocytes and slightly chemotactic for neutrophils. MPIF-1 has been shown to inhibit colony formation of bone marrow myeloid immature progenitors. It has also been attributed to an inhibitory activity on hematopoietic progenitor cells. MPIF-1 is a ligand for the chemokine receptor CCR1.
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Molecular Weight
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11.3 kDa, observed by reducing SDS-PAGE.
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Purity
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> 95% as analyzed by SDS-PAGE.
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Storage
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Lyophilized recombinant Human MPIF/CCL23 (aa46-120) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Human MPIF/CCL23 (aa46-120) should be stable up to 1 week at 4°C or up to 3 months at -20°C.
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