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Product
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MCP-3/CCL7, Mouse
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Cat#
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101-27-60A
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Sequence
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QPDGPNASTC CYVKKQKIPK RNLKSYRRIT SSRCPWEAVI
FKTKKGMEVC AEAHQKWVEE AIAYLDMKTP TPKP
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Unit/Weight
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2 μg
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Unit Price
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$58.00
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Description
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Monocyte Chemotactic Protein-3 (MCP3) and CCL7 are two monocyte chemotactic proteins. Both MCP3 and CCL7 are members of the CC family of chemokines and share 62% and 71% amino acid sequence identity, respectively, with MCP1. CCL7 also shares 58% amino acid identity with MCP3. Similarly to other CC chemokines, all three MCP proteins are monocyte chemoattractants. In addition, the three MCPs can chemoattract activated NK cells as well as CD4+ and CD8+ T lymphocytes. All three cytokines have also been shown to attract eosinophils and induce histamine secretion from basophils.
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Molecular Weight
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Approximately 8.5 kDa, a single, non-glycosylated polypeptide chain containing 74 amino acids.
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Purity
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> 95 % by SDS-PAGE and HPLC analyses.
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Storage
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This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C. Avoid repeated freeze/thaw cycles.
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