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Product
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C10/CCL6, Mouse
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Cat#
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101-27-57C
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Sequence
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GLIQEIEKED RRYNPPIIHQ GFQDTSSDCC FSYATQIPCK
RFIYYFPTSG GCIKPGIIFI SRRGTQVCAD PSDRRVQRCL STLKQGPRSG
NKVIA
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Unit/Weight
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1 mg
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Unit Price
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$2093.00
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Description
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Chemokine (C-C motif) ligand 6 (CCL6) is a small cytokine belonging to the CC chemokine family that has only been identified in rodents. Murine C10 is expressed in myelopoietic bone marrow cultures when stimulated with GM-CSF, M-CSF, IL-3 or IL-4. It signals primarily through the CCR1 receptor. C10 is chemotactic for B cells, CD4+ T cells, monocytes and NK cells and also exhibits powerful suppressive activity on colony formation by different lineages of hematopoietic progenitors. The C10 contains the four highly conserved cysteine residues present in CC chemokines.
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Molecular Weight
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Approximately 10.7 kDa, a single non-glycosylated polypeptide chain containing 95 amino acids.
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Purity
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> 97 % by SDS-PAGE and HPLC analyses.
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Storage
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This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C. Avoid repeated freeze/thaw cycles.
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