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Product
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Eotaxin/CCL11, Mouse
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Cat#
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101-27-51A
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Sequence
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HPGSIPTSCC FIMTSKKIPN TLLKSYKRIT NNRCTLKAIV
FKTRLGKEIC ADPKKKWVQD ATKHLDQKLQ TPKP
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Unit/Weight
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20 μg
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Unit Price
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$152.00
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Description
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Eotaxin also called CCL11 is a CC chemokine that signals through the CCR3 receptor. It is produced by IFN-gamma stimulated endothelial cells and TNF-activated monocytes. Eotaxin selectively chemoattracts eosinophils and along Eotaxin-2 and Eotaxin-3, plays a key role in the regulation of eosinophil recruitment in the asthmatic lung, and in allergic reactions.
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Molecular Weight
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Approximately 8.4 kDa, a single non-glycosylated polypeptide chain containing 74 amino acids.
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Purity
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> 96 % by SDS-PAGE and HPLC analyses.
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Storage
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This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C. Avoid repeated freeze/thaw cycles.
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