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Product
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MCP-2/CCL8, Mouse
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Cat#
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101-27-39A
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Sequence
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GPDKAPVTCC FHVLKLKIPL RVLKSYERIN NIQCPMEAVV
FQTKQGMSLC VDPTQKWVSE YMEILDQKSQ ILQP
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Unit/Weight
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20 μg
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Unit Price
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$152.00
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Description
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MCP-2 and MCP-3 are two recently identified monocyte chemotactic proteins produced by human MG-63 osteosarcoma cells. Both MCP-2 and MCP-3 are members of the C-C family of chemokines and share 62% and 71% amino acid sequence identity, respectively, with MCP-1. MCP-3 also shares 58% amino acid identity with MCP-2.Similarly to other C-C chemokines, all three MCP proteins are monocyte chemoattractants. In addition, the three MCPs can chemoattract activated NK cells as well as CD4+ and CD8+ T lymphocytes. All three cytokines have also been shown to attract eosinophils and induce histamine secretion from basophils.
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Molecular Weight
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Approximately 8.5 kDa, a single, non-glycosylated polypeptide chain containing 74 amino acids.
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Purity
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> 97 % by SDS-PAGE and HPLC analyses.
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Storage
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This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C. Avoid repeated freeze/thaw cycles.
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