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Product
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Eotaxin-2/CCL24, Human
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Cat#
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101-27-33A
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Sequence
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VVIPSPCCMF FVSKRIPENR VVSYQLSSRS TCLKAGVIFT
TKKGQQFCGD PKQEWVQRYM KNLDAKQKKA SPRARAVA
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Unit/Weight
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20 μg
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Unit Price
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$152.00
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Description
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Eotaxin, also named MPIF-2 and Ck?, is a novel CC chemokine recently identified. It is produced by activated monocytes and T lymphocytes. Eotaxin-2 selectively chemoattracts cells expressing CCR3 including eosinophils, basophils, Th2 T cells, mast cells, and certain subsets of dendritic cells. Additionally, Eotaxin-2 inhibits the proliferation of multipotential hematopoietic progenitor cells. The mature protein, which also includes a C-terminal truncation, contains 78 amino acid residues (92 a.a. residues for the mouse homolog, without C-terminal truncation).
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Molecular Weight
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Approximately 8.8 kDa, a single non-glycosylated polypeptide chain containing 78 amino acids.
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Purity
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> 97 % by SDS-PAGE and HPLC analyses.
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Storage
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This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C. Avoid repeated freeze/thaw cycles.
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