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Product
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MIP-3α/CCL20, Human
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Cat#
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101-27-25A
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Sequence
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ASNFDCCLGY TDRILHPKFI VGFTRQLANE GCDINAIIFH
TKKKLSVCAN PKQTWVKYIV RLLSKKVKNM
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Unit/Weight
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20 μg
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Unit Price
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$152.00
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Description
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MIP-3 alpha/CCL20, also known as LARC (Liver and Activation-regulated Chemokine) and as Exodus, is a CC chemokine that is expressed in the liver, lymph nodes, appendix, PBL and lung and can signal through the CCR6 receptor. MIP-3 alpha is chemotactic towards lymphocytes and dendritic cells. Additionally, it promotes the adhesion of memory CD4+ T cells and inhibits colony formation of bone marrow myeloid immature progenitors.
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Molecular Weight
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Approximately 8.0 kDa, a single non-glycosylated polypeptide chain containing 70 amino acids.
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Purity
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> 97 % by SDS-PAGE and HPLC analyses.
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Storage
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This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C. Avoid repeated freeze/thaw cycles.
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