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Product
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MCP-3/CCL7, Human
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Cat#
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101-27-08B
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Sequence
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QPVGINTSTT CCYRFINKKI PKQRLESYRR TTSSHCPREA
VIFKTKLDKE ICADPTQKWV QDFMKHLDKK TQTPKL
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Unit/Weight
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1 mg(2x500 μg)
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Unit Price
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$2093.00
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Description
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MCP2 and CCL7 are two monocyte chemotactic proteins produced by human MG63 osteosarcoma cells. Both MCP2 and CCL7 are members of the CC family of chemokines and share 62% and 71% amino acid sequence identity, respectively, with MCP1. CCL7 also shares 58% amino acid identity with MCP2.Similarly to other CC chemokines, all three MCP proteins are monocyte chemoattractants. In addition, the three MCPs can chemoattract activated NK cells as well as CD4+ and CD8+ T lymphocytes. All three cytokines have also been shown to attract eosinophils and induce histamine secretion from basophils.
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Molecular Weight
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Approximately 9.0 kDa, a single, non-glycosylated polypeptide chain containing 76 amino acids.
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Purity
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> 97 % by SDS-PAGE and HPLC analyses.
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Storage
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This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C. Avoid repeated freeze/thaw cycles.
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