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Product
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RANTES/CCL5, Human
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Cat#
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101-27-06B
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Sequence
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SPYSSDTTPC CFAYIARPLP RAHIKEYFYT SGKCSNPAVV
FVTRKNRQVC ANPEKKWVRE YINSLEMS
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Unit/Weight
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1 mg
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Unit Price
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$2093.00
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Description
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CCL5 or RANTES (acronym for Regulated upon Activation, Normal T cell Expressed and presumably Secreted), was initially discovered by subtractive hybridization as a transcript expressed in T cells but not B cells. Eosinophilchemotactic activities released by thrombinstimulated human platelets have also been purified and found to be identical to RANTES. Besides T cells and platelets, RANTES has been reported to be produced by renal tubular epithelium, synovial fibroblasts and selected tumor cells.
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Molecular Weight
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Approximately 7.8 kDa, a single non-glycosylated polypeptide chain containing 68 amino acids.
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Purity
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> 98 % by SDS-PAGE and HPLC analyses.
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Storage
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This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C. Avoid repeated freeze/thaw cycles.
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