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Product
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Human PDGF-1
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Cat#
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101-1-22A
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Sequence
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His-Tag sequence not included: SIEEAVPAVC KTRTVIYEIP RSQVDPTSAN FLIWPPCVEV KRCTGCCNTS SVKCQPSRVH HRSVKVAKVE YVRKKPKLKE VQVRLEEHLE CACATTSLNP DYREEDTDVR
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Unit/Weight
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0.01 mg
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Unit Price
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$228.00
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Description
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The term ‘PDGF’ refers to a family of disulphide bond linked dimeric isoforms that act as autocrine and paracrine growth factors and are released by platelets. They act as potent mitogens for almost all mesenchymally-derived cells. Aberrant expression is involved in certain cancers, fibroproliferative disorders, and atherosclerosis. PDGF proteins also contribute to wound healing and neural regeneration. There are four members of the PDGF family – PDGF A, PDGF B, PDGF C and PDGF D. PDGF-A is expressed as a short form that is soluble and a long form that is retained by the extracellular matrix. Recombinant PDGF-A comprises a 110 amino acid fragment (87-196) corresponding to the mature PDGF-A short chain protein and is expressed in E. coli with an amino-terminal hexahistidine tag.
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Molecular Weight
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17.02 kDa
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Purity
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Purity > 95% as determined by reducing and non-reducing SDS-PAGE, Bradford assay, Western blot and ELISA.
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Storage
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Store at -20°C. Product is guaranteed one year from the date of shipment.
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