Human IL-1 beta
Product   Human IL-1 beta
Cat#   101-13-177A
Sequence   His-Tag sequence not included: APVRSLNCTL RDSQQKSLVM SGPYELKALH LQGQDMEQQV VFSMSFVQGE ESNDKIPVAL GLKEKNLYLS CVLKDDKPTL QLESVDPKNY PKKKMEKRFV FNKIEINNKL EFESAQFPNW YISTSQAENM PVFLGGTKGG QDITDFTMQF VSS
Unit/Weight   0.01 mg
Unit Price   $228.00
Description   Interleukin-1 beta (IL-1 beta) is produced by activated macrophages. This cytokine stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 beta proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. Recombinant IL-1 beta comprises a 153 amino acid fragment (117-269) corresponding to the mature IL-1 beta chain and is expressed in E. coli with an amino-terminal hexahistidine tag.
Molecular Weight   21.88 kDa
Purity   Purity > 95% as determined by reducing and non-reducing SDS-PAGE, Bradford assay, Western blot and ELISA.
Storage   Store at -20°C. Product is guaranteed one year from the date of shipment.