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Product
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Human IL-16
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Cat#
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101-13-167A
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Sequence
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MPDLNSSTDS AASASAASDV SVESTAEATV CTVTLEKMSA GLGFSLEGGK GSLHGDKPLT INRIFKGAAS EQSETVQPGD EILQLGGTAM QGLTRFEAWN IIKALPDGPV TIVIRRKSLQ SKETTAAGDS
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Unit/Weight
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0.01 mg
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Unit Price
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$228.00
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Description
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Interleukin-16 (IL-16 or Lymphocyte Chemoattractant Factor) is produced primarily by CD4(+) and CD8(+) T cells and acts as a chemoattractant for lymphocytes, monocytes, eosinophils, dendritic cells and Langerhans cells. Additionally, IL-16 has been reported to upregulate IL-2 receptor (CD25), induce progression of cells to the G(1) phase and suppresses HIV & SIV replication. Other cells which have been shown to express IL-16 are; B-cells, eosinophils, macrophages, epithelial cells, fibroblasts, microglial cells and keratinocytes. Human and Murine IL-16 share a high degree of structural and functional similarity. Recombinant Human IL-16 is comprised of 130 amino acids with a MW of 13.5 kDa.
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Molecular Weight
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13500 Da
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Purity
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Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
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Storage
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Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
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