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Product
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Human IL-17F
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Cat#
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101-13-163A
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Sequence
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MRKIPKVGHT FFQKPESCPP VPGGSMKLDI GIINENQRVS MSRNIESRST SPWNYTVTWD PNRYPSEVVQ AQCRNLGCIN AQGKEDISMN SVPIQQETLV VRRKHQGCSV SFQLEKVLVT VGCTCVTPVI HHVQ
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Unit/Weight
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0.025 mg
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Unit Price
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$228.00
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Description
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Interleukin-17F (IL-17F) is one of six members of the IL-17 family (IL-17A-F) secreted by activated CD4+ T cells and monocytes. Similar to IL-17A, IL-17F binds to the IL-17RC receptor and promotes the production of IL-6, IL-8, G-CSF and increases cartilage matrix turnover rates. IL-17F is also thought to inhibit angiogenesis and induce endothelial cells to produce IL-2, MCP-1 and TGF-beta1. Recombinant Human IL-17F is a non-glycosylated protein consisting of two 134 amino acid polypeptide chains linked by disulfide bridges with a MW of 30 kDa. The recombinant protein corresponds to full-length IL-17F and has cytokine production activity on mouse cells.
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Molecular Weight
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30062 Da
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Purity
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Purity Approximately 97% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm. Quantitation on SDS-PAGE against a known standard.
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Storage
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Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
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