Product
|
Human IL-22
|
Cat#
|
101-13-158A
|
Sequence
|
MAPISSHCRL DKSNFQQPYI TNRTFMLAKE ASLADNNTDV RLIGEKLFHG VSMSERCYLM KQVLNFTLEE VLFPQSDRFQ PYMQEVVPFL ARLSNRLSTC HIEGDDLHIQ RNVQKLKDTV KKLGESGEIK AIGELDLLFM SLRNACI
|
Unit/Weight
|
0.01 mg
|
Unit Price
|
$228.00
|
Description
|
Interleukin-22 (IL-22 or IL-TIF) was first identified by its ability to induce IL-9 production in mast cells and T-cells. IL-22 is expressed in CD23 activated T-cells and many organs upon LPS stimulation. IL-22 signals via the IL-22R and IL-10R-beta receptors. Recombinant human IL-22 is produced in E. coli as a non-disulfide-linked homodimeric non-glycosylated polypeptide chain containing 2 x 146 amino acids with a MW of 33,607 Da.
|
Molecular Weight
|
33607 Da
|
Purity
|
Purity > 97% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
|
Storage
|
Store at -20C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
|