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Product
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Human IL-33
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Cat#
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101-13-154A
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Sequence
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MSITGISPIT EYLASLSTYN DQSITFALED ESYEIYVEDL KKDEKKDKVL LSYYESQHPS NESGDGVDGK MLMVTLSPTK DFWLHANNKE HSVELHKCEK PLPDQAFFVL HNMHSNCVSF ECKTDPGVFI GVKDNHLALI KVDSSENLCT ENILFKLSET
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Unit/Weight
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0.01 mg
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Unit Price
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$228.00
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Description
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Interleukin-33 (IL-33) binds to IL1RL1/ST2 and activates a signaling pathway involving MYD88, IRAK1, IRAK4 and TRAF6 followed by phosphorylation of MAP kinases. IL-33 induces T helper type-2 associated cytokines. Recombinant Human IL-33 produced in E. coli is a non-disulfide-linked homodimeric non-glycosylated polypeptide chain consisting of 160 amino acids with a MW of 18,125 Da.
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Molecular Weight
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18125 Da
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Purity
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Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm. Quantitation on SDS-PAGE against a known standard.
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Storage
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Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
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