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Product
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Human IL-35
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Cat#
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101-13-151A
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Sequence
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His-Tag sequence not included: RKGPPAALTL PRVQCRASRY PIAVDCSWTL PPAPNSTSPV SFIATYRLGM AARGHSWPCL QQTPTSTSCT ITDVQLFSMA PYVLNVTAVH PWGSSSSFVP FITEHIIKPD PPEGVRLSPL AERQLQVQWE PPGSWPFPEI FSLKYWIRYK RQGAARFHRV GPIEATSFIL RAVRPRARYY VQVAAQDLTD YGELSDWSLP ATATMSLGK
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Unit/Weight
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0.01 mg
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Unit Price
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$228.00
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Description
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Interleukin-35 (IL-35) is a member of the IL-12 cytokine family and exists as a dimeric protein composed of IL-12 p35 and IL-27EIB chains. The heterodimer has been reported to be an anti-inflammatory cytokine suppressing the immune response through the expansion of regulatory T cells and suppression of Th17 cell development. Recombinant IL-35 comprises a 209 amino acid fragment (21-229) corresponding to the IL-35EIB subunit and is expressed in E. coli with an amino-terminal hexahistidine tag.
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Molecular Weight
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27.81 kDa
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Purity
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Purity > 95% as determined by reducing and non-reducing SDS-PAGE, Bradford assay, Western blot and ELISA.
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Storage
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Store at -20°C. Product is guaranteed one year from the date of shipment.
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