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Product
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Human IL-6 Soluble Receptor
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Cat#
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101-13-148A
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Sequence
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His-Tag sequence not included: LAPRRCPAQE VARGVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGS HPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLL VDVPPEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLL VRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSSFYI VSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVAR NPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVI HDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPWTESR SPPAENEVSTPMQALTTNKDDDNILFRDSANATSLPVQ
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Unit/Weight
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0.01 mg
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Unit Price
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$228.00
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Description
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The interleukin-6 receptor (IL-6R) complex is composed of two membrane glycoproteins: the low affinity receptor and the signal transducing component. The soluble form of IL-6R (IL6-sR) is found in the urine of healthy adult humans and the serum of HIV positive individuals, as well as in the cell culture supernatants of stimulated PBMC. This soluble form of IL-6R results from either proteolytic cleavage from the membrane, or an isoform derived splice variant. Recombinant IL6-sR comprises a 161 amino acid fragment (20-357) corresponding to the mature IL6-sR protein and is expressed in E. coli with an amino-terminal hexahistidine tag.
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Molecular Weight
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42.25 kDa
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Purity
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Purity > 95% as determined by reducing and non-reducing SDS-PAGE, Bradford assay, Western blot and ELISA.
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Storage
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Store at -20°C. Product is guaranteed one year from the date of shipment.
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