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Product
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Human Inhibin Alpha
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Cat#
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101-13-143A
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Sequence
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His-Tag sequence not included: STPLMSWPWS PSALRLLQRP PEEPAAHANC HRVALNISFQ ELGWERWIVY PPSFIFHYCH GGCGLHIPPN LSLPVPGAPP TPAQPYSLLP GAQPCCAALP GTMRPLHVRT TSDGGYSFKY ETVPNLLTQH CACI
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Unit/Weight
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0.01 mg
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Unit Price
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$228.00
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Description
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Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, and embryonic axial development or bone growth (depending on their subunit composition). Inhibins appear to oppose the functions of activins. Inhibins are dimeric proteins, linked by one or more disulfide bonds. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B. Recombinant inhibin alpha subunit comprises a 134 amino acid fragment (233-366) corresponding to the mature inhibin alpha subunit protein and is expressed in E. coli with an amino-terminal hexahistidine tag.
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Molecular Weight
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19.20 kDa
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Purity
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Purity > 95% as determined by reducing and non-reducing SDS-PAGE, Bradford assay, Western blot and ELISA.
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Storage
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Store at -20°C. Product is guaranteed one year from the date of shipment.
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