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Product
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Human MCP-4
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Cat#
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101-13-133A
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Sequence
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QPDALNVPST CCFTFSSKKI SLQRLKSYVI TTSRCPQKAV IFRTKLGKEI CADPKEKWVQ NYMKHLGRKA HTLKT
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Unit/Weight
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0.02 mg
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Unit Price
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$228.00
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Description
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Monocyte chemoattractant protein 4 (MCP-4 or C-C motif chemokine 13) is a chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. MCP-4 signals through CCR2B and CCR3 receptors. This protein plays a role in the accumulation of leukocytes in allergic and non-allergic inflammation. MCP-4 is involved in the recruitment of monocytes into the arterial wall during process of atherosclerosis. This protein also plays a role in monocyte attraction in tissues chronically exposed to exogenous pathogens. Recombinant Human MCP-4 produced in E. coli is a non-glycosylated polypeptide chain containing 74 amino acids with a MW of 8,510 Da.
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Molecular Weight
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8510 Da
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Purity
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Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
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Storage
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Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
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