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Product
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Human MCSF
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Cat#
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101-13-132A
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Sequence
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MEEVSEYCSHMIGSGHLQSLQRLIDSQMETSCQITFEFVDQE QLKDPVCYLKKAFLLVQDIMEDTMRFRDNTPNAIAIVQLQELSL RLKSCFTKDYEEHDKACVRTFYETPLQLLEKVKNVFNETKNLLD KDWNIFSKNCNNSFAECSSQGHERQSEGS
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Unit/Weight
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0.01 mg
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Unit Price
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$228.00
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Description
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Macrophage colony stimulating factor (M-CSF) is one of the glycoproteins called colony-stimulating factors (CSFs). Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood: the granulocytes and the monocytes-macrophages. M-CSF is synthesized by mesenchymal cells. This cytokine stimulates the survival, proliferation, and differentiation of hematopoietic cells of the monocyte-macrophage series. Some clinical investigations have shown autologous production of M-CSF various human cell lines in vitro and by tumors in vivo. Recombinant Human M-CSF produced in E. coli is a disulfide linked homodimer, non-glycosylated, polypeptide chain containing 2 x 159 amino acids with a MW of 36.8 kDa.
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Molecular Weight
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36800 Da
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Purity
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Purity > 97% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
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Storage
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Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
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