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Product
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Human MIP-1-alpha
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Cat#
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101-13-130A
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Sequence
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ASLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPGV IFLTKRSRQV CADPSEEWVQ KYVSDLELSA
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Unit/Weight
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0.02 mg
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Unit Price
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$228.00
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Description
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Macrophage inflammatory protein 1-alpha (MIP-1-alpha or C-C motif chemokine 3) is a monokine with inflammatory and chemokinetic properties. MIP-1-alpha binds to CCR1, CCR4, and CCR5, and is one of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HOV-1, HIV-2, and simian immunodeficiency virus (SIV). Recombinant Human MIP-1 produced in E. coli is a single non-glycosylated polypeptide chain containing 70 amino acids with a MW of 7,820 Da.
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Molecular Weight
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7820 Da
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Purity
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Purity > 97% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
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Storage
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Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
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