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Product
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Human MIP-3-beta
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Cat#
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101-13-127A
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Sequence
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GTNDAEDCCL SVTQKPIPGY IVRNFHYLLI KDGCRVPAVV FTTLRGRQLC APPDQPWVER IIQRLQRTSA KMKRRSS
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Unit/Weight
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0.02 mg
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Unit Price
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$228.00
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Description
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Macrophage inflammatory protein 3 beta (MIP-3-beta or C-C motif chemokine 19) is a cytokine that plays a role in inflammatory and immunological responses as well as normal lymphocyte recirculation and homing. MIP-3-beta also is important in T-cell trafficking in the thymus, and T-cell and B-cell migration to secondary lymphoid organs. MIP-3-beta specifically binds to the chemokine receptor CCR7. Recombinant MIP-3-beta shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Human MIP-3b produced in E. coli is a single non-glycosylated polypeptide chain containing 77 amino acids with a MW of 8,809 Da.
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Molecular Weight
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8809 Da
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Purity
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Purity > 98% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
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Storage
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Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
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