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Product
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Human TIMP-1
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Cat#
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101-13-98A
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Sequence
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His-Tag sequence not included: CTCVPPHPQT AFCNSDLVIR AKFVGTPEVN QTTLYQRYEI KMTKMYKGFQ ALGDAADIRF VYTPAMESVC GYFHRSHNRS EEFLIAGKLQ DGLLHITTCS FVAPWNSLSL AQRRGFTKTY TVGCEECTVF PCLSIPCKLQ SGTHCLWTDQ LLQGSEKGFQ SRHLACLPRE PGLCTWQSLR SQIA
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Unit/Weight
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0.01 mg
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Unit Price
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$228.00
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Description
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Tissue inhibitor of metalloproteinase 1 (TIMP-1) is an inducible glycoprotein, which is synthesized by many different cell types. TIMP-1 binds in a reversible fashion to matrix metalloproteinases, with regions in the N-terminal domain binding to the MMP substrate-binding site. TIMP-1 stimulates erythropoiesis and inhibits apoptosis in B-cells. Recombinant TIMP-1 comprises a 184 amino acid fragment (24-207) corresponding to the mature TIMP-1 protein and is expressed in E. coli with an amino-terminal hexahistidine tag.
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Molecular Weight
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25.21 kDa
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Purity
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Purity > 95% as determined by reducing and non-reducing SDS-PAGE, Bradford assay, Western blot and ELISA.
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Storage
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Store at -20°C. Product is guaranteed one year from the date of shipment.
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