Product
|
Mouse FLT-3 Ligand
|
Cat#
|
101-13-80A
|
Sequence
|
MTPDCYFSHS PISSNFKVKF RELTDHLLKD YPVTVAVNLQ DEKHCKALWS LFLAQRWIEQ LKTVAGSKMQ TLLEDVNTEI HFVTSCTFQP LPECLRFVQT NISHLLKDTC TQLLALKPCI GKACQNFSRC LEVQCQPDSS TLLPPRSPIA LEATELPEPR PRQ
|
Unit/Weight
|
0.01 mg
|
Unit Price
|
$228.00
|
Description
|
Fms-related tyrosine kinase receptor 3 ligand (Flt3 ligand, FLT3LG) binds to Fms-Like Tyrosine Kinase-3 (FLT-3). Mouse FLT3 ligand stimulates the proliferation of cells expressing mouse FLT-3 receptors. The effects of FLT-3 ligand are synergized by coexpression of G-CSF, GM-CSF, M-CSF, IL3 and SCF. FLT-3 ligand promotes long-term expansion and differentiation of mouse pro-B-cells in the presence of IL7 or in combination of IL7 and IL3. Recombinant Mouse Flt3-Ligand produced in E. coli is a non-glycosylated polypeptide chain containing 144 amino acids with a MW of 16,431 Da.
|
Molecular Weight
|
16431 Da
|
Purity
|
Purity > 98% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
|
Storage
|
Store at -20C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
|