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Product
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Mouse FLT-3 Ligand
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Cat#
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101-13-46A
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Sequence
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MTPDCYFSHS PISSNFKVKF RELTDHLLKD YPVTVAVNLQ DEKHCKALWS LFLAQRWIEQ LKTVAGSKMQ TLLEDVNTEI HFVTSCTFQP LPECLRFVQT NISHLLKDTC TQLLALKPCI GKACQNFSRC LEVQCQPDSS TLLPPRSPIA LEATELPEPR PRQ
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Unit/Weight
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0.01 mg
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Unit Price
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$228.00
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Description
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Fms-related tyrosine kinase receptor 3 ligand (Flt3 ligand, FLT3LG) binds to Fms-Like Tyrosine Kinase-3 (FLT-3). Mouse FLT3 ligand stimulates the proliferation of cells expressing mouse FLT-3 receptors. The effects of FLT-3 ligand are synergized by coexpression of G-CSF, GM-CSF, M-CSF, IL3 and SCF. FLT-3 ligand promotes long-term expansion and differentiation of mouse pro-B-cells in the presence of IL7 or in combination of IL7 and IL3. Recombinant Mouse Flt3-Ligand produced in E. coli is a non-glycosylated polypeptide chain containing 144 amino acids with a MW of 16,431 Da.
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Molecular Weight
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16431 Da
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Purity
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Purity > 98% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
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Storage
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Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
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