Mouse THPO
Product   Mouse THPO
Cat#   101-13-13A
Sequence   SPVAPACDPR LLNKLLRDSH LLHSRLSQCP DVDPLSIPVL LPAVDFSLGE WKTQTEQSKA QDILGAVSLL LEGVMAARGQ LEPSCLSSLL GQLSGQVRLL LGALQGLLGT QLPLQGRTTA HKDPNALFLS LQQLLRGKVR FLLLVEGPTL CVRRTLPTTA VPSSTSQLLT LNKF
Unit/Weight   0.01 mg
Unit Price   $228.00
Description   Thrombopoietin (THPO) is a lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development, and plays a major role in the physiological regulating of circulating platelets. Recombinant Mouse TPO produced in E. coli is a single non-glycosylated soluble polypeptide chain containing 174 amino acids with a MW of 18,704 Da which comprises the receptor binding domain of the Mpl-ligand protein.
Molecular Weight   18704 Da
Purity   Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
Storage   Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.