Product
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TLR11 Antibody
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Cat#
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100-23-15A
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Unit/Weight
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100 μg
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Unit Price
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$311.00
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Species Reactivity
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M
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Tested Application(s)
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E, WB, ICC
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Brief Description
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(CT) Toll-like receptor protein
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Specific Description
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Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (4,5). TLR11 is one of three mouse TLRs that lack a human ortholog (6). It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system (7).
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Storage
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TLR11 antibody can be stored at 4°C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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