Product
|
MTCH2 Antibody
|
Cat#
|
100-2-100A
|
Unit/Weight
|
100 μg
|
Unit Price
|
$311.00
|
Species Reactivity
|
H
|
Tested Application(s)
|
E, WB, IHC
|
Brief Description
|
Mitochondrial carrier homolog 2
|
Specific Description
|
Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. MTCH2 is a member of the mitochondrial carrier protein family that catalyze the exchange of substrates across the inner mitochondrial membrane and is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals, suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway.
|
Storage
|
MTCH2 antibody can be stored at 4°C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
|
|