 With the rapid growth of the protein drug market and recent advances in proteomics, the demand for large quantities of pure, active proteins has been increasing. Pepmic is fully equipped to meet this demand for large-scale protein production service. Our versatile and reliable protein expression platforms, include fermentors, wave mixers, and bioreactors, which accommodate different scales of protein production, from milligrams to a few hundreds grams. Our large scale protein production services, typically coupled with our large scale protein purification services, have delivered more than 500 proteins, including those at the scale of 100 grams from a single project.
Capability Specifications
Bacteria
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Transformed bacterial culture for large-scale fermentation, up to 1,000L.
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Provides homogeneous recombinant proteins, over 98% pure, for crystallization, and partially purified recombinant proteins, over 70% pure.
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Provides large quantities of protein, up to several grams
Yeast
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Yeast culture up to 1,000L for large-scale fermentation.
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Provides homogeneous recombinant proteins, over 98% pure, for crystallization.
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Provides partially purified recombinant proteins, over 70% pure.
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Provides large quantities of protein, up to grams.
Baculovirus-Insect Cells
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High titer recombinant baculovirus stock carrying the customer's gene.
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Provides homogeneous recombinant proteins, over 98% pure, for crystallization.
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Provides partially purified recombinant proteins, over 70% pure.
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Provides a large scale protein production option, up to few hundreds of mg, using insect cells and a wave mixer system.
Mammalian Cells
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Provides one single system for the production of final homogeneous recombinant proteins; from gene synthesis to expression; for orders of up to 100mg.
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Permits transient expression of customers' proteins of interest, up to 10mg in 10 days.
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Provides conditioned media and cell pellets from stable cell lines, up to 500L, using a wave mixer system.
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